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Anabolic steroids reduce good cholesterol and elevate bad cholesterol, leading to a higher risk of cardiovascular events," said Dr. Michael Siegel, MD, author of the study and an associate professor of cardiovascular medicine at the Harvard T.H. Chan School of Public Health. "It's critical to have guidelines for the use of these drugs before it gets out of hand. But patients who are already using them need to know that it's an option and not necessarily an answer to all their health problems."In the new study, published Feb. 28 in JAMA Internal Medicine, researchers focused on a group of more than 5500 men and women who had high levels of levels of testosterone. These men and women were followed for five years.They found:Men who took steroids had nearly three times the risk of the heart attack and stroke compared to those who had received niacin, a vitamin B-1 supplement.People who had taken steroids had nearly two and a half times the risk of cardiovascular events compared to those who were taking niacin.Men who had used steroids showed a 23 percent increase in all-cause mortality and 14 percent increase in cardiovascular death compared to those who had been treated for low testosterone levels with niacin.In men who reported that their testosterone levels were in the normal range, men who had taken steroids showed increases in all-cause mortality and increased risk of cardiovascular events."More men are taking steroids, so it's important we educate them about this," said Siegel. "We need studies to look at all of the side effects that occur with steroids. The study should help inform doctors."However, this shouldn't prompt doctors to recommend using steroids just for the purposes of muscle building."Steroids, like any drug, should not be used in place of an established treatment," Siegel said. "The study was designed to help us decide whether the use of steroids is warranted."For more information on prostate cancer, visit the website of U.S. PSA.Similar articles: